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Vehicles for human transport that have two wheels and require balancing by the rider date back to the early 19th century. The first means of transport making use of two wheels arranged consecutively, and thus the archetype of the bicycle, was the German draisine dating back to The term bicycle was coined in France in the s, and the descriptive title ” penny farthing “, used to describe an ” ordinary bicycle “, is a 19th-century term. Augusto Marinoni, a lexicographer and philologist, who was entrusted by the Commissione Vinciana of Rome with the transcription of Leonardo’s Codex Atlanticus. The first verifiable claim for a practically used bicycle belongs to German Baron Karl von Drais , a civil servant to the Grand Duke of Baden in Germany. Drais invented his Laufmaschine German for “running machine” in , that was called Draisine English or draisienne French by the press. Karl von Drais patented this design in , which was the first commercially successful two-wheeled, steerable, human-propelled machine, commonly called a velocipede , and nicknamed hobby-horse or dandy horse. Hans-Erhard Lessing Drais’s biographer found from circumstantial evidence that Drais’s interest in finding an alternative to the horse was the starvation and death of horses caused by crop failure in , the Year Without a Summer following the volcanic eruption of Tambora in
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A coronavirus vaccine could be widely available to much of the American public as early as April of next year, Operation Warp Speed chief Dr Moncef Slaoui told Business Insider in an exclusive interview. His program aims to have a shot anytime between then and June, which Dr Slaoui believes will make it possible to life to return to some semblance of normality by the second half of next year. Data on whether or not the six leading vaccine candidates appear to work should be available by the end of the year, he said.
Of course, Dr Slaoui has skin in the game. A former executive at GlaxoSmithKline GSK , which is making working on one of the vaccines, Dr Slaoui only accepted the position in the Trump administration task force on the condition he got to keep his shares in his former company. A vaccine may be ready by then, but that doesn’t mean everyone will get it, even if it’s available to the public.
Dr Anthony Fauci said on Wednesday that there will not be a federal mandate that the general public get vaccinated during a talk with George Washington University. Operation Warp Speed Chief pictured told Business Insider that an exact timeline is impossible to predict, but that his initiative could know by year-end if a coronavirus shot works, have it available to the general public as early as April, and get the US back to something like normal by late next year. Both Moderna and Pfizer are in late-stage trials, meaning that, if all goes well, they could have data on whether or not their coronavirus shots work by October and ready to apply for Food and Drug Administration FDA approval.
That would mean their shots could be ready to ship as early as the end of the year or beginning of next. Merck is also making a coronavirus vaccine, but lags behind the other four candidates. Everything hinges on the data from those trials. If they show the shots are safe and at least somewhat effective – Dr Fauci has said he’d settle for a shot that was 50 percent effective at blocking coronavirus – then the process of allocation and getting the shots to health workers, at-risk Americans and then the general public can begin in earnest.
Developing a safe and effective shot is really only half the battle, however.
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This post was contributed by a community member. The views expressed here are the author’s own. After leaving my husband seven years ago, I found myself in this scary world of dating. How do people meet one another in the 21st century when you are now in your 30s and have two small children? Do you scour through thousands of on line profiles only to find all profiles are sounding exactly the same? I am going to sort out for you the different ways in Connecticut that you can meet not only members of the opposite gender, but also social and networking opportunities.
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Road Course Race at Daytona: Boston, MA driver Kaz Grala gets 7th: Manchester, CT’s Joe takes 9th. LaJoie is the son of Norwalk, CT native Randy LaJoie who earned two Xfinity It is Elliott’s third consecutive road course win dating back to last year. Average Speed of Race Winner: mph.
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